Straumann® Dental Implant System 的表面 

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从行业标杆 SLA® 到高性能 SLActive® 种植体表面,Straumann 不断提高要求以设立骨结合的新标准。为 Straumann® PURE 纯瓷种植体而开发的 ZLA® 延续了这一传统。

纤维蛋白网的 SEM 图片,由 Empa 提供,拍摄于 2016 年

Straumann® SLActive®

性能超乎想象。

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SLActive® 是 Straumann 出品的极具促愈合潜力的高性能表面。它代表着高度的可预测性和快速的骨结合1-8。 最近的研究显示,即使面对极富挑战性的治疗方案和健康状况不佳的患者,SLActive® 种植体也能表现出非凡的临床性能。9-11

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可预测性

即刻负重种植体的 10 年期成活率:98.2%9

骨结合

在所有适应症中,愈合期从 6-8 周缩短至 3-4 周。*

生物学

即使在缺陷部位也能促进骨再生。12

性能

在接受过放射治疗的骨状况不良患者中 5 年后种植体成活率:100%10.11

* 与 SLA® 相比。适应症:从单牙缺失到无牙颌。

纤维蛋白网的 SEM 图片,由 Empa 提供,拍摄于 2016 年

Straumann® SLA®

在日常医务中持久耐用且高效。

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经典的 SLA® 表面于 1998 年推出,以大颗粒喷砂工艺为基础,产生大粗糙度的钛表面。后又通过酸蚀打造微粗糙度外层。得到的表面形貌是供细胞附着的理想结构。大量经同行评审的临床和临床前研究都已证实其强大的长期性能和可靠性,因此它是牙科种植领域中有文献证实的最佳表面之一。根据一项独立研究,使用其他竞争品牌种植体系统的患者发生种植体周围炎的风险,比使用 SLA® 表面的 Straumann® 种植体的患者要高三倍多。13

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成活率

经过 5 年和 10 年跟进后,不同的研究一致证实其成活率极高,介于 95.1% 和 98.8% 之间。14-20

骨保护

10 年后平均骨吸收量为 0.5-1 mm(以种植体负重时间为基线)。15,16

种植体周围炎患病率低

10 年跟进期内种植体周围炎患病率极低 (1.8%)。15

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参考文献

SLActive® 1 Straumann SLActive implants compared to Straumann SLA implants.Lang NP, Salvi GE, Huynh-Ba G, Ivanovski S, Donos N, Bosshardt DD.Early osseointegration to hydrophilic and hydrophobic implant surfaces in humans.Clin Oral Implants Res.2011 Apr;22(4):349-56. doi: 10.1111/j.1600-0501.2011.02172.x.2 Rupp F, Scheideler L, Olshanska N, de Wild M, Wieland M, Geis-Gerstorfer J. Enhancing surface free energy and hydrophilicity through chemical modification of microstructured titanium implant surfaces.Journal of Biomedical Materials Research A, 76(2):323-334, 2006. 3 De Wild M. Superhydrophilic SLActive® implants.Straumann document 151.52, 2005; Katharina Maniura.Laboratory for Materials – Biology Interactions Empa, St. Gallen, Switzerland, Protein and blood adsorption on Ti and TiZr implants as a model for osseointegration.EAO 22nd Annual Scientific Meeting, October 17 – 19 2013, Dublin.Kopf BS, Schipanski A, Rottmar M, Berner S, Maniura-Weber K, Enhanced differentiation of human osteoblasts on Ti surfaces pre-treated with human whole blood.Acta Biomaterialia.2015 June; 19: 180–190.Kopf BS, Ruch S, Berner S, Spencer ND, Maniura-Weber K, The role of nanostructures and hydrophilicity in osseointegration: In-vitro protein-adsorption and blood-interaction studies.J Biomed Mater Res A. 2015 August; 103 (8): 2661-2672. 4 Schwarz, F., et al., Bone regeneration in dehiscence-type defects at non-submerged and submerged chemically modified (SLActive®) and conventional SLA® titanium implants: an immunohistochemical study in dogs.J Clin.Periodontol.35.1 (2008): 64–75.5 Rausch-fan X, Qu Z, Wieland M, Matejka M, Schedle A. Differentiation and cytokine synthesis of human alveolar osteoblasts compared to osteoblast-like cells (MG63) in response to titanium surfaces.Dental Materials 2008 Jan;24(1):102-10.Epub 2007 Apr 27.6 Schwarz F, Herten M, Sager M, Wieland M, Dard M, Becker J. Histological and immunohistochemical analysis of initial and early osseous integration at chemically modified and conventional SLA® titanium implants: Preliminary results of a pilot study in dogs.Clinical Oral Implants Research, 11(4): 481-488, 2007.7 Raghavendra S, Wood MC, Taylor TD.Int. J. Oral Maxillofac.Implants.2005 May–Jun;20(3):425–31.9.8 Oates TW, Valderrama P, Bischof M, Nedir R, Jones A, Simpson J, Toutenburg H, Cochran DL.Enhanced implant stability with a chemically modified SLA® surface: a randomized pilot study.Int. J. Oral Maxillofac.Implants.2007;22(5):755–760.9 Nicolau P, Guerra F, Reis R, Krafft T, Benz K , Jackowski J 10-year results from a randomized controlled multicenter study with immediately and early loaded SLActive implants in posterior jaws.Presented at 25th Annual Scientific Meeting of the European Association of Osseointegration – 29 Sep – 1 Oct 2016, Paris.10 Nelson, K., Stricker, A., Raguse, J.-D. and Nahles, S. (2016), Rehabilitation of irradiated patients with chemically modified and conventional SLA implants: a clinical clarification.J Oral Rehabil, 43: 871–872. doi:10.1111/joor.12434.11 Patients treated with dental implants after surgery and radio-chemotherapy of oral cancer.Heberer S, Kilic S, Hossamo J, Raguse J-D, Nelson K. Rehabilitation of irradiated patients with modified and conventional sandblasted, acid-etched implants: preliminary results of a split-mouth study.Clin.Oral Impl.Res.22, 2011; 546–551.12 Straumann (2016).SLActive® supports enhanced bone formation in a minipig surgical GBR model with coronal circumferential defects.Unpublished data. SLA® 13 Buser D, Janner SF, Wittneben JG, Bragger U, Ramseier CA, Salvi GE.10-year survival and success rates of 511 titanium implants with a sandblasted and acid-etched surface: a retrospective study in 303 partially edentulous patients.Clin Implant Dent Relat Res.2012 Dec;14(6):839-51.14 Fischer K, Stenberg T.: Prospective 10-year cohort study based on a randomized controlled trial (RCT) on implant-supported full-arch maxillary prostheses.Part 1: sandblasted and acid-etched implants and mucosal tissue.Clin Implant Dent Relat Res.2012 Dec;14(6):808-15.15 van Velzen FJ, Ofec R, Schulten EA, Ten Bruggenkate CM,.10-year survival rate and the incidence of peri-implant disease of 374 titanium dental implants with a SLA surface: a prospective cohort study in 177 fully and partially edentulous patients.Clin Oral Implants Res.2015 Oct;26(10):1121-8.16 Cochran DL, Jackson JM, Bernard JP, ten Bruggenkate CM, Buser D, Taylor TD, Weingart D, Schoolfield JD, Jones AA, Oates TW Jr. A 5-year prospective multicenter study of early loaded titanium implants with a sandblasted and acid-etched surface.Int J Oral Maxillofac Implants.2011 Nov-Dec;26(6):1324-32.17 Cochran D, Oates T, Morton D, Jones A, Buser D, Peters F. Clinical field trial examining an implant with a sand-blasted, acid-etched surface.J Periodontol.2007 Jun;78(6):974-82.18 Bornstein MM, Schmid B, Belser UC, Lussi A, Buser D. Early loading of non-submerged titanium implants with a sandblasted and acid-etched surface.5-year results of a prospective study in partially edentulous patients.Clin Oral Implants Res.2005 Dec;16(6):631-8.19 Roccuzzo M1, Aglietta M, Bunino M, Bonino L. Early loading of sandblasted and acid-etched implants: a randomized-controlled double-blind split-mouth study.Five-year results.Clin Oral Implants Res.2008 Feb;19(2):148-52.20 Derks J, Schaller D, Håkansson J, Wennström JL, Tomasi C, Berglundh T. Effectiveness of Implant Therapy Analyzed in a Swedish Population: Prevalence of Peri-implantitis.J Dent Res.2016 Jan;95(1):43-9. doi ZLA® 21 Bormann KH, Gellrich NC, Kniha H, Dard M, Wieland M, Gahlert M. Biomechanical evaluation of a microstructured zirconia implant by a removal torque comparison with a standard Ti-SLA implant.Clin Oral Implants Res.2012 Oct;23(10):1210-6. doi: 10.1111/j.1600-0501.2011.02291.x.Epub 2011 Nov 14. 22 Gahlert M, Roehling S, Sprecher CM, Kniha H, Milz S, Bormann K. In vivo performance of zirconia and titanium implants: a histomorphometric study in mini pig maxillae.Clin Oral Implants Res.2012 Mar;23(3):281-6. doi: 10.1111/j.1600-0501.2011.02157.x.Epub 2011 Aug 2.23 Gahlert M1, Röhling S, Wieland M, Eichhorn S, Küchenhoff H, Kniha H A comparison study of the osseointegration of zirconia and titanium dental implants.A biomechanical evaluation in the maxilla of pigs.Clin Implant Dent Relat Res.2010 Dec;12(4):297-305. doi: 10.1111/j.1708-8208.2009.00168.x.

ZLA® 23 Roehling S, Astasov-Frauenhoffer M, Hauser-Gerspach, Braissant O, Woelfler H, et a., In Vitro Biofilm Formation On Titanium And Zirconia Implant Surfaces, J Periodontol.2016 Oct 7:1-16.[Epub ahead of print] DOI: 10.1902/jop.2016.160245